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Across 1. A classic symptom of DVT, pain behind the knee with dorsiflexion of the foot, is referred to as ___ sign 5. Drug therapy with this hormone increases the risk of Thromboembolic disease 7. A clot in the cardiovascular system 11. Vitamin K antagonist 12. This med is ineffective in TED because it elicits its action on the arterial system, not the venous system 15. How the "hirudin" type thrombin inhibitors are adjusted 17. If Vitamin K admin is necessary, PO route is preferred over IV route because it lacks the risk of this 18. Potential side effect of heparin 20. One of the biggest contraindications to anticoagulation 21. LMWH has better bioavailability in this route than UFH

Down 2. A key factor to a sustained therapeutic INR is minimizing the intake of this 3. Lab used for heparin monitoring 4. How argatroban, a non "hirudin" thrombin inhibitor, is adjusted 6. A classic sign of PE (latin term) 8. Routine monitoring parameters for LMWH 9. Drug of choice during pregnancy for VTE prophylaxis 10. A non-pharmacological intervention for VTE prophylaxis 13. Preferred method of heparin administration 14. Factor Xa inhibitors such as this med are beneficial due to their absence of HIT cross-reactivity 16. Agent used to reverse heparin in case of major bleeding 19. A detached thrombus