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Across 2. growth period of a cell during which chromosomes are duplicated 3. uncontrolled cell division and death cuased by the interaction between environmental factors and changes in the production of enzymes involved in the cell cycle 4. continuous sequence of growth and division of a cell, which is controlled by key enzymes 11. final stage of mitosis during which the two daughter cells become separated 13. cell structure that joins two sister chromatids of a chromosome

Down 1. identical halves of the duplicated parent chromosome formed before the onset of cell division; these exact copies are joined at a centromere 3. pair of cylindrical structures composed of microtubules that duplicate during interjphase and move to opposite ends of the cell during prophase 5. cell structure that carries the genetic material 6. thin fiber structure that forms between the two poles or centrioles during prophase and shortens during anaphase pulling the sister chromatids apart 7. second stage of mitosis in which chromosomes move to the equator of the spindle and chromatids are each attached by centromeres to a separate spindle fiber 8. first phase of mitosis during which chromatin coils to form visible chromosomes 9. stage of mitosis during which the centromeres split and sister chromatids are pulled apart to opposite poles of the cell 10. cell division during which chromosomes are equally distributed to the two identical daughter cells that are formed 12. segment of DNA located on the chromosome; directs protein production that controls the cell cycle