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Across 1. are general and provide protect against broad pathogens 3. a soft bilobed structure enclosed in a connective tissue capsule and located anterior to the aorta and the upper part of the sternum 6. the largest lymphatic organ 7. absence of spleen 9. cell mediated immunity 11. a disease causing agent 14. defense mechanisms targeting specific pathogens 15. structural units of lymph nodes 17. is a type of antibody that develops in the blood plasma in response to contact with certain antigens in foods or bacteria 18. commonly found in exocrine gland secretions 19. antibody mediated immune response 21. large globular proteins 22. horomone like peptides 23. proteins, polysaccharides, glycoproteins 24. complex network of chambers and channels through which lymph circulates

Down 2. when the receipents immune system doesn't recongnize the donor cells and attacks it. 4. inflammation of the spleen 5. antigens that trigger allergic responses 8. damaged tissue may form a thick fluid 9. a group of proteins in plasma & other body fluids 10. elevated body temperature 12. produces an active immunity 13. skin & mucous membrane linings that prevent entry of some infectious agents 16. larger lymphatic vessels lead to specialized organs 17. a tissue response to injury or infection 19. indented region of the node 20. tumor composed of lymphatic tissue