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Pharm exam #2

Neal

Amitryptiline, imipramine, Desi-Ramin, nortriptyline NE, DA, 5HT receptor antagonist
Donepezil, rivastigmine and tacrine GABAergic signaling; atypical AD used as an antipsychotic. Does not lead to increased levels of neurotransmitters
Sumatriptan AED Ca2+ channel blocker used for bipolar disease
Eptinezumab/galcanezumab Monoamine Oxidase Inhibitor
Fluoxetine, trazodone, paroxetine, sertraline, cítalopram, escitalopram Serotonin antagonist that inhibits release of CGRP
Maprotiline + mirtrazapine 5HT + Norepinephrine re uptake inhibitor
Bupropion 5HT + NE re up take inhibitor
Duloxetine, amoxapine, venlafaxine Replaces Na+ in nerve cell and inhibits Ca2+ mediated release of NE/DA
Isocarboxazid, phenelzine, tranylcypromine AED Na+ channel blocker used for bipolar disease
St. John’s Wort Missing phrase2 - 16
Lithium Atypical anti-psychotics; “weak antagonists at D1,2, 3, 5” + strong antagonist @ D4
Carbamazepine Cholinesterase inhibitor (anticholinesterase)
Valproic Acid Monoclonal antibody that antagonizes CGRP
Clonazepam Rapid onset of psychomotor inhibition which may be life saving in case of violent or psychotic patient
Lamotrigine Tricyclic antidepressant
Lurasidone Norepinephrine re uptake inhibitor
Olanzapine Butyrophenone (DA receptor blockade)
Aripiprazole  Norepinephrine + Dopamine + 5HT reuptake inhibitor
Zulpresso Selective serotonin reuptake inhibitor
Chlorpromazine, fluphenazine, thioridazine, trifluoperazine AED GABAergic used for bipolar disease
Haloperidol AED Na+ channel blocker used for bipolar disease
Clozapine, risperidone, olanzapine, quietapine, aripiprazole Phenothiazine anti-psychotic medications; block DA receptors

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