1 | Alpha-Amanitan | | _____ | blocks NADH-Q oxidoreductase |
2 | Actinomycin D | | _____ | block the proton pore of the ATPase |
3 | Rifampicin | | _____ | Death Cap, RNA polymerases 2&3, microfilament stabilized, gastric lavage |
4 | Tetracyclines | | _____ | blocks the passage of electrons through the cytochrome b-c1 complex |
5 | Chloramphenicol | | _____ | intercalates and stops transcription elongation |
6 | Erythromycin | | _____ | inhibits peptidyl transferase activity of 50S subunit |
7 | Diptheria | | _____ | combine with cytochrome oxidase and blocks the transfer of electrons to oxygen |
8 | NSAIDs | | _____ | inhibits bacterial RNA polymerase |
9 | Montelukast | | _____ | sodium channel blocker created by some fish/amphibians |
10 | Tetrodotoxin | | _____ | DNA replication inhibitor, nucleotide lacking 3' OH group |
11 | Saxitoxin | | _____ | DNA replication inhibitor, intercalating agent |
12 | Dideoxynucleotides | | _____ | binds to 50S subunit and inhibits translocation |
13 | Ethidium | | _____ | inhibits ANT |
14 | AZT | | _____ | DNA replication inhibitor, HIV reverse transcriptase, thymine lacking 3' OH group |
15 | Nalidixic acid and Cipro | | _____ | inhibits formation of proxaglandins and thromboxanes |
16 | Daunorubicin, Etoposide | | _____ | inhibits bacterial DNA gyrases |
17 | 5-fluorouracil | | _____ | modifies side-chain of ribosome (EF2), blocking translocation of growing peptide chain |
18 | Rotenone | | _____ | inhibits thymidylate synthase needed for synthesis of dTMP (anti-cancer) |
19 | Antimycins | | _____ | block the proton pore of the ATPase |
20 | Cyanide/CO poisoning | | _____ | inhibits luekotriene formation |
21 | Bonkrekic Acid | | _____ | inhibits topoisomerase 2 (anti-cancer) |
22 | Dicyclohexylcarbodiimide (DCCD) | | _____ | bind to 30S subunit and inhibit binding of aminoacyltRNAs |
23 | Oligomycin | | _____ | sodium channel blocker created by dinoflagellate of clams/mussels |