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Across 1. A type of white blood cell that contains a knobbly nucleus and engulfs pathogens. _______________ (9) 4. These are the cell types in the blood that make up the immune system. _____________ ________________ _______________ (5,5,5) 5. A type of white blood cell that contains a large round nucleus and makes antibodies. __________________ (10) 7. All pathogens contain their own type of these on their surface. _______________ (7) 8. When you body has developed memory lymphocytes after an illness or vaccine you are said to be _____________. (6) 9. Antibodies are very ____________. They only stick to matching antigens. (8) 11. When phagocytes meet a pathogen they don't eat it, they ___________ it. (6) 12. A organism that causes disease. _________________ (8)

Down 2. These are made by lymphocytes. They recognise and stick to pathogens to destroy them. __________________(10) 3. Once you are immune, the next time the pathogen invades, the production of antibodies is f____________ _______ b____________ (6,3,6) 6. A dead or weakened pathogen or piece of pathogen designed to activate specific lymphocytes to make antibodies. _______________ (7) 10. When the body is infected with a pathogen, this activates specific lymphocytes to produce antibodies. Some of these lymphocytes stay behind after the infection to act as _____________ lymphocytes ready to attack the pathogen if it invades again. (6)