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Across 3. Single or group of purple violet, non-refractile masses eccentrically located w/in the RBC (2 Words) 8. Production of red blood cells 11. RBCs with 3-12 blunt-ended spicules (thorn-like projections) on their outer edges 12. A hormone produced and released by the kidney and found in plasma that stimulates the production of red blood cells by the bone marrow 13. Normal size 14. Nucleated RBC & Cytoplasm is larger in area compared to the nucleus 15. Nucleus stains a deeper blue-purple, with a “wagon-wheel” pattern & Cytoplasm stains blue-gray to pink-grey; polychromatophilic 16. Evenly distributed rounded short “goose bumps” over the RBC surface 17. Non-nucleated, biconcave disc, Normocytic, Normochromic (2 Words) 18. Most immature, Nucleus is large, round to slightly oval; fine chromatin pattern & Cytoplasm appears as a band around nucleus 19. Not biconcave like normal RBC, Has a small surface area (microcytic) 20. Appear as a target shape, showing a centrally-stained area (2 Words)

Down 1. Oval-shaped RBCs 2. Are inclusions within red blood cells composed of denatured hemoglobin (2 Words) 4. Nucleus is relatively large, round or slightly oval & Cytoplasm amount is slightly increased from the blast stage, Intensely basophilic (royal blue) 5. Major deviation from normal shape 6. Any variation in size outside normal RBC diameter 7. RBCs in the shape of a sickle or a crescent (2 Words) 9. RBC fragments 10. Describes the central zone of pallor, normal biconcave disc that is thinner at the central portion. 18. As an RBC matures it lightens due to a decrease in ?, which has an affinity for methylene blue