Across 1. the macromolecular machine that segregates chromosomes to two daughter cells during mitosis 7. an orderly set of stages that take place between the time a eukaryotic cell divides and the time the resulting daughter cells also divide 9. programmed cell death 11. the stage before DNA replication

Down 2. division of cytoplasm 3. a protein that stops the cell cycle at the G1 checkpoint when DNA is damaged 4. cell performs it's usual functions 5. follows the S stage, in this stage the cell synthesizes proteins that will assist cell division 6. follows the G1 stage, its when the DNA synthesis or replication occurs 8. nuclear division 10. protein responsible for interpreting cell growth signals and also nutrient availability signals