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Across 3. atropine, antihistamines, and sympathomimetics may ______ cholinergic drugs 5. considered an antidote for anticholingergic poisoning and poisoning by irreversible cholinesterase inhibitors 6. this should be kept to record daily dosages of drugs and ADLs to help provide information for caregivers 8. primary adverse effects of cholinergic drugs are a consequence of over stimulation of ____ 15. located postsynaptically in smooth muscle, cardiac muscle and glands 18. carbachol, policarpine and echothiophate 20. used in patients with Parkinson's who also have dementia 21. most of the cholinergic agonists have _____ adverse effects that include severe GI disturbances 22. drug allergy, GI or GU tract obstruction, bradycardia, defects in cardiac impulse conduction, hyperthyroidism, epilepsy, hypotension, or COPD

Down 1. mimic the action of acetylcholine 2. bethanechol should not be used if this is suspected 4. is preferred over pharmacologicals to treat anticipated postoperative decrease of bowel peristalsis and/or urinary retention 7. binds acetycholine and mediates its actions 8. cholingergic drugs are also known as this 9. neurotransmitter responsible for the transmission of nerve impulses to effector cells in the parasympathetic nervous system 10. indirect acting cholinergic drugs are also used to treat 11. primarily effects GI tract, bladder and eye 12. are located in the ganglia of both the parasympathetic and sympathetic nervous systems 13. the only orally administered direct acting cholinergic drug 14. circulatory collapse, hypotension, bloody diarrhea, shock and cardiac arrest are signs of 16. is commonly used to diagnose myasthenia gravis 17. cholinergic drugs causes ______ salivation and sweating 19. bethanechol also causes the sphincters in the bladder and GI tract to _____