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Across 1. located in a very small bony chambers called lacunae 5. multinucleated cells called _____________ break down the calcified extracellular matrix. 6. on the outer surface,the articulating portion of the epiphsis is coated with a layer of hyaline cartilage 7. most bones of skeleton, and they develop from masses of hyaline cartilage shape 8. fat storage tissue found in certain bone cavities 10. has a continuous extracellular matrix with no spaces 17. cancellous bone with thin layers of compact bone on their surface 18. blood cell formation

Down 1. develops spaces and canals that enlager, the bone is easily fracture and break because it cannot support the body weight. 2. flat bome of skull 3. cavity containing marrow within the diaphysis of a long bone 4. chemical substances that lack carbon and hydrogen 7. a band of cartilage called... 9. at the end of a bone is an expanded portion, which articulates with another bone 11. the formation of bone tissue 12. the shaft of the bone, which is located between the epiphyses 13. a tough, vascular covering of fibrous tissue 14. blood-cell forming tissue in spaces within bones 15. primitive connective tissue cells enlager and differentiate into bone-forming cells 16. the main strucyural protein