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Across 2. Vitamin B6 is needed for the synthesis of ___, the cells responsible for controlling our immune response. 5. There is insufficient data to establish a ________ level for pantothenic acid consumption. 6. Manganese can be found in whole grains, nuts, and ____________. 7. ________ is essential to the production of ATP from glucose 9. A deficiency of B12 causes ___________. 10. Anemia can occur in patients with vitamin B6 deficiency due to impaired _________ synthesis. 14. The nervous system relies on the presence of vitamin B6 for the formation of ______________ and the myelin sheath. 15. Choline is needed in the body for the synthesis of what neurotransmitter? 17. Folate coenzymes are needed for the synthesis of what? 18. __________ is a disease caused by thiamin deficiency resulting in lethargy, fatigue, and other neurological symptoms. 19. The two sulfur-containing amino acids that are needed for protein synthesis are ___________ and cysteine. 20. Choline deficiency in adults can cause fatty ______ and muscle damage. 21. Biotin deficiency is uncommon but can be a result in the malabsorption of biotin due to an increase in the protein, ______, found in raw egg whites 22. ____ made from niacin is used as an electron carrier in reactions that synthesize fatty acids and cholesterol 24. The synthesis of methionine from homocysteine inhibits the its accumulation in the blood which in turn decreases the risk of cardiovascular disease. B12, B6 and _______ are involved in this reaction. 28. Riboflavin forms flavin mononucleotide (FMN), which along with FMN acts as what in the electron transport chain? 30. Biotin functions in energy metabolism as a necessity to make four-carbon molecule needed in the citric acid cycle and in _______________. 31. What is the best source of riboflavin in the North American Diet? 32. __________ affects the poor who cannot afford a varied diet and consume corn as a dietary staple. 33. Wernicke-Korsakoff Syndrome occurs in __________ and characterized by deficiency in thiamin causing mental confusion, psychosis, memory disturbances, and coma. 34. More than half of the iodine in the body is located in what gland? 35. The most obvious outward sign of iodine deficiency is ____, which is the enlargement of the thyroid gland. 36. Manganese functions as a constituent and activator of ___________.

Down 1. Most of the iodine in the North American diet comes from what? 3. Vitamin B12 can be converted into methylcobalamin and adenosylcobalamin, which are ___________ that function in important metabolic reactions. 4. If folate levels are low during early pregnancy, there is an increased risk of what in the fetus? 8. _______ is a coenzyme for a group of enzymes that add the acid group COOH to molecules. 11. _______ has two forms nicotinic acid and nicotinamide. Both can be used by the body to make the two active enzymes NAD and NADP. 12. The human body needs choline for the structure and function of cell membranes and lipid ___________. 13. Sulfur can be found in inorganic food preservatives which are used as ____________. 16. Symptoms of a riboflavin deficiency that cause inflammation of the eyes, lips, mouth and tongue. 17. Chromium deficiency symptoms include impaired glucose tolerance with ____ -like symptoms. 18. If folate intake is high it can mask symptoms caused by a deficiency in which other vitamin? 19. An excess of this mineral results in damage to the nervous system. 23. An organic food source of sulfur is ___________. 25. Meat, eggs, whole grains, and legumes are _____ in pantothenic acid. 26. _________ of pantothenic acid is rare due to its wide distribution in foods 27. After absorption, chromium is bound to the iron transport protein ____ for transport in the blood. 29. Chromium is needed for the normal utilization of this monosaccharide.