1							2
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5														6
		7
8							9									10
					11
		12
				13															14
	15
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	17									18

Across 1. Forms meshwork at site of platelet plug (6) 4. Converts firbrinogen (factor I) to fibrin (8) 5. Form plug (9) 7. Activates Thrombin (factor II) (11) 8. Thrombin Activates which clotting factor? (4) 11. Healthy Endothelium releases _______ and nitric acid (12) 12. Factor XIII _______ fibrin meshwork (10) 15. Active factor XII AKA _________ Factor (7) 16. Plasminogen is formed by the _____ (5) 17. There are _____ intrinsic steps in the clotting cascade. (5) 18. Which ions are involved in at least 4 steps of the clotting cascade? (7)

Down 1. Activation of _____ triggers the clotting cascade (9) 2. Aggregating platelets secrete ADP and ________ (13) 3. Adenosine Diphosphate (3) 6. Blood ______ is the transformation of blood from liquid into solid gel (11) 8. The hageman factor activates the ____ factor (2) 9. Activates factor XII and platelets at site of wound (8) 10. ADP positvely feeds back to both platelets and _________ 13. There are _____ clotting factors (6) 14. There are _____ extrinsic steps in the clotting cascade (4)