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Across 1. Caused by loss of gastric parietal cells which are responsible, in part, for the secretion of intrinsic factor. 3. Genetic disorders that impair the body's ability to control blood clotting. 5. Decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. 7. Cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells. 9. Formation of a blood clot iside a blood vessel, obstructing the flow of blood through the circulatory system. 10. Decrease of platelets in blood 11. Red blood cells that assume an abnormal, rigid, sickle shape. 12. A collection of blood outside the blood vessels.

Down 2. Caused by insufficient dietary intake and absorption of iron. 4. Bone marrow does not produce sufficient new cells to replenish blood cells. 6. lodging an embolus into a narrow capillary vessel of an arterial bed which causes a blockage. 8. Proportion of blood volume that is occupied by red blood cells increases.